• Natural Orifice Translumenal Endoscopic Surgery (NOTES)
• Wound Healing
• The Bariatric Population
• Robotic Surgery
• GERD, Barrett's Esophagus, and Esophageal Cancer
• Pancreatic Cancer
• Hernia Prevention and Treatment
• Surgical Training
• For Patients

OSUMC investigations into postsurgical pain and wound healing include a prospective study to address the association between postsurgical pain intensity and subsequent healing of a biopsy wound. This study extended the previous laboratory models of wound healing to a surgical population, providing the first evidence that pain plays in important role in postsurgery wound healing, a key variable in postsurgical recovery.

Laboratory models include a porcine model of diabetes to study wound healing.

This is a collaborative effort between Chandan Sen, PhD, and W. Scott Melvin, MD. Sen is a professor of Molecular and Biochemistry; Melvin is a Professor of Surgery and Director of the CMIS.

Wound Healing References

Fries RB, Wallace WA, Roy S, Kuppusamy P, Bergdall V, Gordillo GM, Melvin WS, Sen CK. Dermal excisional wound healing in pigs following treatment with topically applied pure oxygen. Mutat Res 2005 Nov 11;579(1-2):172-181.

McGuire L, Heffner K, Glaser R, Needleman B, Malarkey W, Dickinson S, Lemshow S, Cook C, Muscarella P, Melvin WS, Ellison EC, Kiecolt-Glaser JK. Pain and wound healing in surgical patients. Ann Behav Med 2006 Apr;31(2)-165-172.